1. Nimma Yash (Yash): Known for his role as Rocky in "KGF," Yash has garnered a massive following not only in the South but also nationwide and in Bollywood.

2. Allu Arjun: With his iconic portrayal of Pushpa Raj, Allu Arjun has amassed millions of fans on social media, showcasing the enduring legacy and admiration for South Indian actors.

3. Siva Karthikeyan: A versatile artist in the Tamil film industry, Siva Karthikeyan excels as an actor, producer, singer, TV personality, and lyricist.

4. Pooja Hegde: With appearances in films like "Beast," "Radhe Radhe," and "Kisi Ka Bhai Kisi Ki Jaan," Pooja Hegde's immense beauty and talent have earned her a significant following on Instagram.

5. Ram Charan Teja: Known for his work primarily in Telugu cinema, Ram Charan is admired for his acting prowess, entrepreneurial spirit, and production ventures.

6. Saravanan Sivakumar (Surya): Renowned for his contributions to Tamil cinema, Surya is celebrated as an actor, philanthropist, producer, and TV personality.

7. Mahesh Babu: A prominent figure in Telugu cinema, Mahesh Babu is not only known for his acting but also for his philanthropy and humility, earning him a large fan base.

8. Keerthy Suresh: With her charming looks and innocence, Keerthy Suresh has captured the hearts of many fans, making her one of the most followed South Indian celebrities on Instagram.

9. Dhanush: Known for his iconic roles and memorable performances, Dhanush's popularity and admiration among fans are unparalleled.

10. Jr. NTR (N.T. Rama Rao Jr.): As one of the highest-paid actors in Telugu cinema, Jr. NTR's dignity and fondness among audiences have cemented his status as a top South Indian celebrity on Instagram.

Each of these actors has contributed significantly to the South Indian film industry, earning them a dedicated fan following and admiration on social media platforms like Instagram.